What is LDH (Lactate dehydrogenase)? Low and high LDH

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Lactate dehydrogenase (LDH) is an enzyme that plays an important role in cell metabolism and can be used as one of the markers of cell damage or diseases. Elevated LDH levels can indicate the presence of many different diseases or conditions, but additional tests are required for a definitive diagnosis. Monitoring LDH levels is also important to evaluate the effectiveness of certain medical treatments.

What is LDH (Lactate dehydrogenase)?

Lactate dehydrogenase (LDH) is an enzyme found in many tissues in the body. It is found in high concentrations in tissues such as muscles, liver, kidneys, heart, pancreas and red blood cells. LDH plays an important role in energy production in cells.

What should be the normal value of LDH (Lactate dehydrogenase)?

Normal values ​​of LDH (Lactate Dehydrogenase) vary depending on age and gender. Normal LDH ranges by age are:

  • 0-1 month: 225-600 U/L
  • 1-2 months: 175-425 U/L
  • 3-6 months: 125-350 U/L
  • 6-12 months: 100-300 U/L
  • 1-2 years: 75-250 U/L
  • 3-10 years: 60-200 U/L
  • 11-17 years: 40-175 U/L
  • 18-60 years: 35-160 U/L
  • 61 years and above: 35-190 U/L

What is low LDH (Lactate dehydrogenase)?

Low LDH (Lactate dehydrogenase) means that the level of this enzyme in the blood is lower than normal. This condition is rare and usually not a symptom of a health problem. For the answer to the question of what causes low LDH (Lactate dehydrogenase):

  • vitamin C deficiency
  • copper deficiency
  • muscle weakness
  • Liver failure
  • Kidney failure
  • Side effects of some medications

What is LDH (Lactate dehydrogenase) elevation?

High LDH (Lactate dehydrogenase) means that the level of this enzyme in the blood is higher than normal. This condition may be a symptom of damage to many different tissues or organs. To answer the question of what causes high LDH (Lactate dehydrogenase), these are:

  • Muscle damage (intense exercise, injury, muscle wasting, etc.)
  • liver diseases
  • Heart diseases
  • kidney diseases
  • Pancreatic diseases
  • Hematological diseases
  • infections
  • Side effects of some medications

It is not always possible to prevent high LDH, but high LDH is a condition that needs to be treated because it is a symptom of an underlying disease. To reduce the risk of underlying diseases, it is important to maintain a healthy lifestyle, monitor chronic diseases, cure infections, and have regular health checks.

This information is for informational purposes only. If you have a medical problem, please consult your doctor.

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