The best rune words for every class

In Diablo 4 Vessel of Hatred there are runes that you can combine into rune words to improve your builds. We will therefore show you which are currently the best rune words for each class.

How is the list structured? In our list we show you the best rune words for the strongest builds of each class. You can also check out how the meta is currently developing in our Tier List.

For each class we list the three strongest builds and tell you the rune words that can improve your builds even further. Note that we do not present one runeword per class, as these can vary depending on the build. You can quickly jump to the individual classes using our directory:

In the video you will also find out how the level system has changed in Diablo 4:

Best Rune Words: Spiritborn

Best Rune Words: Barbarian

Best Rune Words: Wizard

Best Rune Words: Druid

Best Rune Words: Hunter

Best Rune Words: Necromancer

Those are all the rune words and alternate runes you should use for the top three class builds in the current meta. Please note that the meta may shift depending on updates. We will therefore adjust our list if the builds change. If you also want to know where you can get the runes from, we have just the right guide for you: Farming Diablo 4 runes: This is the quickest way to find the stones from Vessel of Hatred