Estrogen has the same function as dopamine, the substance in the brain that is imbalanced in ADHD, Kooij explains. “If the estrogen drops, you have twice nothing, so to speak. These substances work on your emotional stability, your overview, your memory, planning and attention. So the ADHD-like things.” After giving birth and after menopause, the level drops so quickly that women with ADHD sometimes “get completely stuck.”