It turned out that painkillers do not relieve the pain, and taking aspirin and ibuprofen as painkillers will make the pain worse and prolong the duration of suffering. For a while, people’s suspicious approach to painkillers and antipyretics has revealed how normal this situation is.
According to the news of the Daily Mail, the research conducted by researchers from McGill University in Canada and Monza Hospital in Italy and published in the journal Science Translational Medicine, was based on tests on human cells and mice in the laboratory environment.
TESTED ON MICE
Anti-inflammatory drugs work by blocking neutrophils, which are white blood cells that help the body begin the healing process.
The experts analyzed blood samples taken three times from 98 people struggling with low back pain. Patients whose pain eventually disappeared had significantly more neutrophils in their blood compared to those who still did.
This inspired the researchers to test blocking neutrophils in injured mice with anti-inflammatory drugs. Most control mice stopped feeling pain within two months.
However, rodents that took the anti-inflammatory drugs experienced pain twice as long, on average, and some suffered up to 10 times longer than the control group.
Repeating the experiment with non-inflammatory pain relievers such as paracetamol did not produce the same long-lasting pain response. This inflammation plays a role in healing injuries and resolving pain, the researchers said.
The findings were supported by a separate analysis of 500,000 people who showed that those who took anti-inflammatory drugs to treat their pain were more likely to have pain two to 10 years later.
WE MUST REVIEW THE TREATMENT METHODS
From Italy Monza Hospital, Dr. Massimo Allegri argued that the findings could mean that paramedics need to treat painful injuries differently.
“Our findings suggest that it is time to reconsider the way we treat acute pain,” Allegri said. Fortunately, the pain can be relieved in other ways that don’t interfere with the inflammation,” he said.
Experts called for more ways to compare anti-inflammatory drugs with other pain relievers that don’t disrupt inflammation. (Spokesman)