The helicopter lost altitude shortly before 3 p.m. local time on Highway 53, about half an hour northwest of the city of Huntsville.
Footage from the scene shows thick, black smoke billowing from the crash site. However, the fire was quickly extinguished.
Emergency medical personnel stated that there were no survivors, although it was not initially known how many were on board. US military officials later said that two people had traveled in the helicopter.
It is not clear what may have caused the accident.