Police, emergency services and ambulance services were called during the night to the E22 just south of Ålem due to an accident with a salt truck.
The driver of the lorry was found underneath the lorry and the E22 was closed in both directions whilst work at the scene continued.
Man dead after the accident
The driver, a 45-year-old man, died in the accident. Relatives have been notified.
The police are investigating the incident as a workplace accident and have drawn up a report on work environment violations.