(Finance) – AENEAS celebrates the International Women’s Day of Science, announcing that a team from you are researchers of his Biomedical Technologies laboratory is developing innovative methodologies for early diagnosis of‘Alzheimer’s.
This is the goal of the MENTAL project which will be realized thanks to donations from taxpayers through the 5×1000 at ENEA. The project, as mentioned, aims to develop non-invasive early diagnosis and low-cost methodologies to be validated in a wider audience of patients to contribute to control of this disease.
The project is based on the recognized association between alterations in the intestinal microbiota with consequent alteration of the molecular characteristics of the fecal sample and the onset of neurodegenerative diseases. Hence the goal of identifying a panel of proteins and /or microRNA through a multi-omic examination (proteome and miRNoma) dfecal samples from patients with varying degrees of Alzheimer’s severity; this latter aspect will be developed in collaboration with the Santa Lucia Foundation in Rome.
“This project has great potential for rapid technology transfer in the biomedical and biotechnological supply chain, to the benefit of citizens and the NHS, which will have access to innovative diagnostic tools. The results obtained will potentially have a strong impact on clinical practice to contribute to the control of a disease. with such a high social impact – underlines Barbara Tanno, scientific manager of MENTAL. To date, in fact, the expectations of prevention, early diagnosis and treatment of this disease, as well as of the main neurological and neurodegenerative pathologies, are almost completely disregarded “.
“MENTAL fits into the broader context of the PNRR 2021-2027 and the Health cluster of Horizon Europe which identify as a priority “the development of new non-invasive prognostic / diagnostic markers of neurodegenerative diseases through research and innovation programs” and, overall, the development of bio-markers of neurodegenerative diseases, through the use of omics sciences, nanotechnologies and new advanced imaging technologies are considered among the priority issues on which to concentrate the economic resources destined for research ”adds Mariateresa Mancuso, Head of the Biomedical Technologies Laboratory.