Stroke, low and medium -income countries are among the most important causes of death and disability, and recurrent events continue to be a major concern. High sodium intake and low potassium intake are considered to be the main risk factors, especially in Northern China. In China, stroke recurrence rates are higher than global averages and reach 17 %in one year and 41 %in five years.
The SSASS trial included 600 villages and 20,995 people in rural China. In previous studies, researchers’ salt of the participants 75 % salt25 %of the potassium chloride substitution.
Jama Cardiology published in the magazine “Salt substitution and recurrent stroke and death: random clinical study” in the study, the team analyzed the data of 15 thousand 249 participants who had previously spent stroke.
The researchers used data from the original study following the safety results, including blood pressure, stroke repetition, mortality, and risk of hyperkalemia. Urine sodium/potassium excretion was also observed.
During the study, the group of 25 %potassium supplements was 14 %less than 14 %of the paralysis compared to the normal salt group; This ratio was the same in the original full cohort study.
During the follow -up, the average systolic blood pressure was lower compared to controls in the salt substitute group. A total of 2,735 recurrent stroke events occurred, 691 fatal and 2,044 non -fatal event.
Hemorrhagic stroke showed a relative decrease by 30 %and the deaths associated with strokes decreased by 21 %. There was no significant difference between the groups in terms of hyperkalemia.
Findings show that salt reduction containing 25 %potassium is a safe, low -cost diet intervention that can reduce stroke recurrence and mortality among paralyzers. Researchers suggest that salt substitutes should be applied more broadly in regions with limited access to high sodium and protective health services.