What is Stiff Person Syndrome? What causes it? Stiff Person Syndrome symptoms and treatment

Stiff person syndrome is characterized by progressive muscle stiffness and frequent painful spasms. This disorder, which affects the central nervous system, manifests itself with neuromuscular symptoms. In the early stages of the syndrome, muscle stiffness and spasms may be transient, but as the disease progresses, these symptoms become permanent. The syndrome can be triggered by a variety of stimuli, and in most cases, no additional neurological symptoms are observed.

What is stiff person syndrome?

Stiff person syndrome is an autoimmune neurological disease characterized by progressive muscle stiffness and spasms, especially in the midsection of the body. Over time, this syndrome causes stiffness in the legs and other muscles, causing spasms. As a result, individuals with stiff person syndrome may have difficulty walking, may be at increased risk of falling, and may be more susceptible to injury. Although there is no cure for the syndrome yet, keeping symptoms under control under the guidance of a specialist can make it easier to cope with the disease.

There are several types of rigid person syndrome: Classic Rigid Person Syndrome, Rigid Person Syndrome Variants, Rigidity and Myoclonus (PERM), and Progressive Encephalomyelitis.

What causes stiff person syndrome?

Stiff person syndrome occurs when the immune system launches an abnormal attack on healthy cells. This condition is usually caused by a deficiency of GABA (gamma-aminobutyric acid). GABA deficiency can be caused by a variety of health problems, such as high blood pressure, diabetes, or liver disease.

What are the symptoms of stiff person syndrome?

Stiff Person Syndrome symptoms include:

  • Stiffness and rigidity due to spasm in the trunk or back area
  • Painful and painful muscle spasms
  • Difficulty walking
  • Risk of injury due to unbalance and falls
  • Shortness of breath if there is spasm in the chest area
  • Chronic pain
  • Constant tension in the muscles
  • Hypersensitivity to sounds
  • Increased sweating over time
  • Feelings of anxiety and worry

How is stiff person syndrome treated?

Treatment for stiff person syndrome varies depending on the severity of symptoms and individual needs. The main goal of the treatment process is to manage symptoms and improve daily living comfort by increasing mobility. The following treatment methods can be applied for stiff person syndrome:

  • Medications and treatments to relieve symptoms
  • Immunotherapies or disease-modifying treatment options
  • Physical medicine and rehabilitation programs
  • Talking Therapies
  • Therapies that support mental health

It is recommended that individuals experiencing rigid person syndrome consult a neurologist to obtain information about the treatment process and determine the most appropriate approach.

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